TIMI IIA

OBJECTIVE: To compare the results of 3 strategies of coronary angiography and angioplasty following intravenous thrombolytic therapy for ST elevation myocardial infarction: immediate invasive, delayed invasive (18-48 h), and a conservative strategy.

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1. Immediate vs delayed catheterization and angioplasty following thrombolytic therapy for acute myocardial infarction. TIMI II A results. The TIMI Research Group. JAMA 1988;260:2849-2858.
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2. Comparison of immediate invasive, delayed invasive, and conservative strategies after tissue-type plasminogen activator. Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II-A Trial. Rogers WJ, Baim DS, Gore JM, Brown BG, Roberts R, Williams DO, Chesebro JH, Babb JD, Sheehan FH, Wackers FJT, Zaret BL, Robertson TL, Passamani ER, Ross R, Knatterud GL, Braunwald E, for the TIMI II-A Investigators. Circulation 1990;81:1457-1476.
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3. Tissue plasminogen activator followed by percutaneous transluminal coronary angioplasty: one-year TIMI phase II pilot results. TIMI Investigators.Chaitman BR, Thompson BW, Kern MJ, et al. Am Heart J 1990;119:213-23.
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4. Announcement of protocol change in thrombolysis in myocardial infarction trial. Braunwald E, Knatterud GL, Passamani ER, Robertson TL. J Am Coll Cardiol 1987;9:467.
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5. Update from the Thrombolysis in Myocardial Infarction Trial. Braunwald E, Knatterud GL, Passamani E, Robertson TL, Solomon R. J Am Coll Cardiol 1987;10:970.
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6. Coronary angioplasty after recombinant tissue-type plasminogen activator in acute myocardial infarction: a report from the Thrombolysis in Myocardial Infarction (TIMI) Trial. Williams DO, Ruocco NA, Forman S. J Am Coll Cardiol 1987;10:45B-50B.
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7. PTCA salvage for thrombolytic failures -implications from TIMI IIA.Baim DS, Diver DJ, Knatterud GL, for the TIMI IIA Investigators. Circulation 1988;78:II-112.
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8. The use of tissue-type plasminogen activator for acute myocardial infarction in the elderly: results from thrombolysis in myocardial infarction Phase I, open label studies and the Thrombolysis in Myocardial Infarction Phase II pilot study. The TIMI Investigators. Chaitman BR, Thompson B, Wittry MD, et al. J Am Coll Cardiol 1989;14:1159-65.
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9. Variables predictive of good functional outcome following thrombolytic therapy in the Thrombolysis in Myocardial Infarction phase II (TIMI II) pilot study. Rogers WJ, Bourge RC, Papapietro SE, et al. Am J Cardiol 1989;63:503-12.
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10. The Thrombolysis in Myocardial Infarction (TIMI) Trial phase II: additional information and perspectives. Baim DS, Braunwald E, Feit F, et al. J Am Coll Cardiol 1990;15:1188-92.
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11. Tissue plasminogen activator followed by percutaneous transluminal coronary angioplasty: one-year TIMI phase II pilot results. TIMI Investigators. Chaitman BR, Thompson BW, Kern MJ, et al. Am Heart J 1990;119:213-23.
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