TIMI 8

TIMI 8 compared the efficacy of hirulog with unfractionated heparin for the treatment among patients presenting with unstable angina and non-Q-wave myocardial infarction.

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Key Study Publications

Antman EM, McCabe CH, Braunwald E. Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: observations from the TIMI 8 trial. The Thrombolysis in Myocardial Infarction. Am Heart J. 2002;143:229-34. Abstract