TIMI 10A

TIMI 10A evaluated the pharmacokinetics, safety and efficacy of several doses of TNK-tPA among patients presenting with acute ST elevation myocardial infarction.

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Key Study Publications

Cannon CP, McCabe CH, Gibson CM, Ghali M, Sequeira RF, McKendall GR, Breed J, Modi NB, Fox NL, Tracy RP, Love TW, Braunwald E. TNK-tissue plasminogen activator in acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI) 10A dose-ranging trial. Circulation. 1997;95:351-6. Abstract