PRINCIPLE-TIMI 44 compared prasugrel versus higher loading and maintenance doses of clopidogrel for inhibiting platelet aggregation in patients undergoing elective percutaneous intervention.


Key Study Publications

Wiviott, S. D., Trenk, D., Frelinger, A. L., O'Donoghue, M., Neumann, F. J., Michelson, A. D., Angiolillo, D. J., Hod, H., Montalescot, G., Miller, D. L., Jakubowski, J. A., Cairns, R., Murphy, S. A., McCabe, C. H., Antman, E. M., Braunwald, E. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial Circulation. 2007;116(25):2923-32. Abstract