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TIMI 18 -  TACTICS Articles

1.    Marc S. Sabatine, MD, MPH, David A. Morrow, MD, MPH, Carolyn H. McCabe, BS, Elliott M. Antman, MD, C. Michael Gibson, MD, MS, and Christopher P. Cannon, MD Combination of quantitative ST deviation and troponin elevation provides independent prognostic and therapeutic information in unstable angina and non–ST-elevation myocardial infarction (Am Heart J 2006 Jan ;151:25- 31.)

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2.    Marc S. Sabatine, MD, MPH; Gavin J. Blake, MD, MPH; Mark H. Drazner, MD, MSc; David A. Morrow, MD, MPH; Benjamin M. Scirica, MD; Sabina A. Murphy, MPH; Carolyn H. McCabe, BS; William S. Weintraub, MD; C. Michael Gibson, MD, MS; Christopher P. Cannon, MD Influence of Race on Death and Ischemic Complications in Patients With Non–ST-Elevation Acute Coronary Syndromes Despite Modern, Protocol-Guided Treatment Circulation. 2005 Mar 15;111:1217-1224.

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3.    Hisham Dokainish, MD, Manu Pillai, MD, Sabina A. Murphy, MPH, Peter M. DiBattiste, MD, Marc J. Schweiger, MD, Amir Lotfi, MD, David A. Morrow, MD, MPH, Christopher P. Cannon, MD, Eugene Braunwald, MD, Nasser Lakkis, MD, for the TACTICS-TIMI-18 Investigators  Prognostic Implications of Elevated Troponin in Patients With Suspected Acute Coronary Syndrome But No Critical Epicardial Coronary Disease A TACTICS-TIMI-18 Substudy Journal American College Cardiology 2005 Jan 4 ;45: 19 –24

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4.    JAMES L. JANUZZI, JR., M.D., JACQUELINE BUROS, B.A., CHRISTOPHER P. CANNON, M.D., ON BEHALF OF THE TACTICS TIMI 18 INVESTIGATORS Peripheral Arterial Disease, Acute Coronary Syndromes, and Early Invasive Management: The TACTICS TIMI 18 Trial Clinical Cardiology 28, 238–242 (2005)

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5.    Juhana Karha, MD, C. Michael Gibson, MS, MD, Sabina A. Murphy, MPH, Peter M. DiBattiste, MD, and Christopher P. Cannon, MD, for the TIMI Study Group Safety of Stress Testing During the Evolution of Unstable Angina Pectoris or Non–ST-Elevation Myocardial Infarction American Journal of Cardiology 2004 Dec 15;94:1537–1539

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6.    Myrvin H. Ellestad, MD Stress Testing: Problems and Appropriate Use in Acute Coronary Syndromes The American Journal of Cardiology Vol. 94 December 15, 2004

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7.    Saihari Sadanandan, MD, Christopher P. Cannon, MD, C. Michael Gibson, MS, MD, Sabina A. Murphy, MPH, Peter M. DiBattiste, MD, Eugene Braunwald, MD, for the TIMI Study Group A Risk Score to Estimate the Likelihood of Coronary Artery Bypass Surgery During the Index Hospitalization Among Patients With Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction Journal of the American College of Cardiology 2004 Aug 18 ;44:799–803

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8.    C. Michael Gibson, MS, MD, Kanwar P. Singh, MD, Sabina A. Murphy, MPH, Peter M. DiBattiste, MD, Laura A. Demopoulos, MD, Christopher P. Cannon, MD, and Eugene Braunwald, MD, for the TIMI Study Group Association Between Duration of Tirofiban Therapy Before Percutaneous Intervention and Tissue Level Perfusion (A TACTICS-TIMI 18 Substudy)American Journal of Cardiology 2004 Aug 15;94:492–494

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9.    Saihari Sadanandan, MD, Christopher P. Cannon, MD, Kasi Chekuri, MD, Sabina A. Murphy, MPH, Peter M. DiBattiste, MD, David A. Morrow, MD, MPH, James A. de Lemos, MD, Eugene Braunwald, MD, C. Michael Gibson, MS, MD Association of Elevated B-Type Natriuretic Peptide Levels With Angiographic Findings Among Patients With Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction Journal of the American College of Cardiology 2004 Aug 4;44:564–8

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10.    Richard G. Bach, MD; Christopher P. Cannon, MD; William S. Weintraub, MD; Peter M. DiBattiste, MD; Laura A. Demopoulos, MD; H. Vernon Anderson, MD; Paul T. DeLucca, PhD; Elizabeth M. Mahoney, ScD; Sabina A. Murphy, MPH; and Eugene Braunwald, MD The Effect of Routine, Early Invasive Management on Outcome for Elderly Patients with Non–ST-Segment Elevation Acute Coronary Syndromes Ann Intern Med. 3 August 2004;141:186-195.

           

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11.    Howard C. Herrmann, MD, Sabina A. Murphy, MPH, Peter M. Dibattiste, MD, Paul T. Delucca, PhD, Laura A. Demopoulos, MD, C. Michael Gibson, MD, and Christopher P. Cannon, MD Greater Benefit of Early Invasive Strategy for Unstable Angina and Non-ST Elevation Myocardial Infarction in United States Compared With Non-United States Patients A TACTICS-TIMI 18 Substudy Critical Pathways in Cardiology June 2004;3: 95–100

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12.    Peter A. McCullough, MD, MPH, C. Michael Gibson, MD, Peter M. DiBattiste, MD, Laura A. Demopoulos, MD, Sabina A. Murphy, PH.D, William S. Weintraub, MD, Franz-Josef Neumann, MD, Sanjay Khanal, MD, Christopher P. Cannon, MD, and for the TACTICS-TIMI-18 Investigators Timing of the Angiography and Revascularization in Acute Coronary Syndromes: An Analysis of the TIMI 18 TACTICS Trial Journal of Interventional Cardiology 2004 Apr; 17:81-86

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13.    Susan A. Mayer, MD, James A. de Lemos, MD, Sabina A. Murphy, MPH, Sandra Brooks, RDCS, Brad J. Roberts, RDCS, and Paul A. Grayburn, MD  Comparison of B-Type Natriuretic Peptide Levels in Patients With Heart Failure With Versus Without Mitral Regurgitation (Am J Cardiol April 15 2004 ;93:1002–1006)

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14.    Stephen D. Wiviott, MD; Christopher P. Cannon, MD; David A. Morrow, MD, MPH; Sabina A. Murphy, BS; C. Michael Gibson, MS, MD; Carolyn H. McCabe, BS; Marc S. Sabatine, MD, MPH; Nader Rifai, PhD; Robert P. Giugliano, SM, MD; Peter M. DiBattiste, MD; Laura A. Demopoulos, MD; Elliott M. Antman, MD; Eugene Braunwald, MD Differential Expression of Cardiac Biomarkers by Gender in Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction A TACTICS-TIMI 18 (Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy–Thrombolysis In Myocardial Infarction 18) Substudy Circulation. 2004 Feb 10;109:580-586.

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15.    Marc S. Sabatine, MD, MPH; David A. Morrow, MD, MPH; Robert P. Giugliano, MD, MS; Sabina A. Murphy, MPH; Laura A. Demopoulos, MD; Peter M. DiBattiste, MD; William S. Weintraub, MD; Carolyn H. McCabe, BS; Elliott M. Antman, MD; Christopher P. Cannon, MD; Eugene Braunwald, MD Implications of Upstream Glycoprotein IIb/IIIa Inhibition and Coronary Artery Stenting in the Invasive Management of Unstable Angina/Non–ST-Elevation Myocardial Infarction A Comparison of the Thrombolysis In Myocardial Infarction (TIMI) IIIB Trial and the Treat angina with Aggrastat and determine Cost of Therapy with Invasive or Conservative Strategy (TACTICS)-TIMI 18 Trial (Circulation. Feb 24 2004;109:874-880.)

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16.    David A. Morrow, MD, MPH, James A. de Lemos, MD, Marc S. Sabatine, MD, MPH, Sabina A. Murphy, MPH, Laura A. Demopoulos, MD,§Peter M. DiBattiste, MD, Carolyn H. McCabe, BS, C. Michael Gibson, MD, MS, FACC, Christopher P. Cannon, MD, FACC, Eugene Braunwald, MD, FACC Evaluation of B-Type Natriuretic Peptide for Risk Assessment in Unstable Angina/Non–ST-Elevation Myocardial Infarction B-Type Natriuretic Peptide and Prognosis in TACTICS-TIMI 18 Journal of the American College of Cardiology 2003 Apr 16;41:1264 –72

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17.    Duane S. Pinto, MD, David P. Lorenz, MD, Sabina A. Murphy, MPH, Susan J. Marble, RN, MS, Peter M. DiBattiste, MD, Laura A. Demopoulos, MD, Christopher P. Cannon, MD, and C. Michael Gibson, MS, MD, for the TIMI Study Group Association of an Activated Clotting Time <250 Seconds With Adverse Event Rates After Percutaneous Coronary Intervention Using Tirofiban and Heparin (A TACTICS-TIMI 18 Substudy) The American Journal of Cardiology Vol. 91 April 15, 2003

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18.    Christopher P. Cannon Small Molecule Glycoprotein IIb/IIIa Receptor Inhibitors as Upstream Therapy in Acute Coronary Syndromes Insights From the TACTICS TIMI-18 Trial Journal of the American College of Cardiology 2003 Feb ;41:43S– 48S

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19.    Ruchira Glaser, MD, Howard C. Hermann, MD, Sabina A. Murphy, MPH Laura A. Demopoulos, MD, Peter M. DiBattiste, MD, Christopher P. Cannon, MD, Eugene Braunwald, MD Benefit of an Early Invasive Management Strategy in Women With Acute Coronary Syndromes JAMA. 2002 Dec 25 ;288:3124-3129

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20.    Marc S. Sabatine, MD, MPH, David A. Morrow, MD, MPH, Christopher P. Cannon, MD, Sabina A. Murphy, MPH, Laura A. Demopoulos, MD, Peter M. DiBattiste, MD, Carolyn H. McCabe, BS, Eugene Braunwald, MD, C. Michael Gibson, MD, MS Relationship Between Baseline White Blood Cell Count and Degree of Coronary Artery Disease and Mortality in Patients With Acute Coronary Syndromes A TACTICS-TIMI 18 Substudy Journal of the American College of Cardiology 2002 Nov 20 ;40:1761– 8

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21.    Elizabeth M. Mahoney, ScD, Claudine T. Jurkovitz, MD, MPH, Haitao Chu, MS, Edmund R. Becker, PhD, Steven Culler, PhD, Andrzej S. Kosinski, PhD, Debbie H. Robertson, RD, MS, Charles Alexander, MD, Soma Nag, MS, John R. Cook, PhD, Laura A. Demopoulos, MD, Peter M. DiBattiste, MD, Christopher P. Cannon, MD, William S. Weintraub, MD, for the TACTICS-TIMI 18 Investigators Cost and Cost-effectiveness of an Early Invasive vs Conservative Strategy for the Treatment of Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction JAMA. 2002 Oct 16;288:1851-1858

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22.    Sorin J. Brener, MD, Sabina A. Murphy, MS, C. Michael Gibson, MD, PhD, Peter M. DiBattiste, MD, Laura A. Demopoulos, and Christopher P. Cannon, MD for the TACTICS-TIMI 18 Investigators Efficacy and Safety of Multivessel Percutaneous Revascularization and Tirofiban Therapy in Patients With Acute Coronary Syndromes The American Journal of Cardiology Vol. 90 September 15, 2002

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23.    James A. de Lemos, MD, David A. Morrow, MD, MPH, C. Michael Gibson, MD, MS, FACC, Sabina A. Murphy, MPH, Marc S. Sabatine, MD, Nader Rifai, PHD, Carolyn H. McCabe, BS, Elliott M. Antman, MD, FACC, Christopher P. Cannon, MD, FACC, Eugene Braunwald, MD, FACC The Prognostic Value of Serum Myoglobin in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes Results From the TIMI 11B and TACTICS-TIMI 18 Studies Journal of the American College of Cardiology 2002 July 17;40:238–44

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24.    Graham C. Wong, MD; David A. Morrow, MD, MPH; Sabina Murphy, MPH; Nicole Kraimer, MS; Rupal Pai, BS; David James, BA; Debbie H. Robertson, RD, MS; Laura A. Demopoulos, MD; Peter DiBattiste, MD; Christopher P. Cannon, MD; C. Michael Gibson, MS, MD; for the TACTICS-TIMI 18 Study Group Elevations in Troponin T and I Are Associated With Abnormal Tissue Level Perfusion A TACTICS-TIMI 18 Substudy Circulation. 2002 July 9 ;106:202-207.

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25.    Nasser Lakkis, MD, Valeri Tsyboulev, MD, C. Michael Gibson, MD, Sabina A. Murphy, MpH, William S. Weintraub, MD, Peter M. DiBattiste, MD, and Christopher P. Cannon, MD for the TACTICS-TIMI-18 Investigators Outcome of Patients With Acute Coronary Syndrome Admitted to Hospitals With or Without Onsite Cardiac Catheterization Laboratory A TACTICS-TIMI 18 Substudy Critical Pathways in Cardiology  2002 • Vol. 1 • No. 4 232-237

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26.    Morrow DA, Cannon CP, Rifai, N, Frey MJ, Vicari R, Lakkis N, Robertson DH, Hille DA, DeLucca PT, DiBattiste PM, Demopoulos LA, Weintraub WS, and Braunwald E  Ability of minor elevations of the Troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and Non-ST Elevation Myocardial Infarction Results From a Randomized Trial JAMA. 2001;286:2405-2412 2001 Nov 21

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27.    CHRISTOPHER P. CANNON, M.D., WILLIAM S. WEINTRAUB, M.D., LAURA A. DEMOPOULOS, M.D., RALPH VICARI, M.D., MARTIN J. FREY, M.D., NASSER LAKKIS, M.D., FRANZ-JOSEF NEUMANN, M.D., DEBBIE H. ROBERTSON, R.D., M.S., PAUL T. DELUCCA, PH.D., PETER M. DIBATTISTE, M.D., C. MICHAEL GIBSON, M.D., AND EUGENE BRAUNWALD, M.D. COMPARISON OF EARLY INVASIVE AND CONSERVATIVE STRATEGIES IN PATIENTS WITH UNSTABLE CORONARY SYNDROMES TREATED WITH THE GLYCOPROTEIN IIb/IIIa INHIBITOR TIROFIBAN New England Journal of Medicine 2001 Jun 21;344:1879-87

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28.    William S. Weintraub, MD, Steven D. Culler, PhD, Andrzej Kosinski, PhD, Edmund R. Becker, PhD, Elizabeth Mahoney, DSc, Joy Burnette, RN, John A. Spertus, MD, David Feeny, PhD, David J. Cohen, MD, Harlan Krumholz, MD, Stephen G. Ellis, MD, Laura Demopoulos, MD, Deborah Robertson, Stephen J. Boccuzzi, PhD, Eliav Barr, MD, and Christopher P. Cannon, MD Economics, Health-Related Quality of Life, and Cost-Effectiveness Methods for the TACTICS (Treat Angina With AggrastatT [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 Trial American Journal of Cardiology 1999 Feb 1;83:317–322

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29.    Invasive Versus Conservative Strategies in Unstable Angina and Non–Q-Wave Myocardial Infarction Following Treatment With Tirofiban: Rationale and Study Design of the International TACTICS-TIMI 18 Trial American Journal of Cardiology 1998 Sep 15;82:731–736